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Phosphoenolpyruvate carboxykinase is a nuclear enzyme in rats and chickens

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1983Publisher:Elsevier BVJournal:International Journal of Biochemistry, volume 15, pages 1,473-1,475 (issn: 0020-711X,

Authors: Gene R. Herzberg; Donald A. Tinker; John T. Brosnan;

doi: 10.1016/0020-711x(83)90081-2

pmid: 6653865

Phosphoenolpyruvate carboxykinase is a nuclear enzyme in rats and chickens

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Abstract

The presence of phosphoenolpyruvate carboxykinase (PEPCK) in the nuclei of chicken liver cells was confirmed using two experimental designs. PEPCK was found to be enriched in the nuclear fraction of rat liver, a species whose hepatic PEPCK is reported to be predominantly cytosolic. We suggest that PEPCK plays a role in nuclear synthesis of N-acetyl-neuraminic acid.

Related Organizations

St. John's University
United States
Memorial University of Newfoundland
Canada

Keywords

Cell Nucleus, Rats, Inbred Strains, DNA, Rats, Glutamate Dehydrogenase, Liver, Species Specificity, Animals, Female, Phosphoenolpyruvate Carboxykinase (GTP), Chickens

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Fields of Science (3) View all

medical and health sciences

basic medicine

Fields of Science

medical and health sciences

basic medicine

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Related to Research communities

UArctic

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