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The Saccharomyces cerevisiae kinetochore

descriptionPublicationkeyboard_double_arrow_right Article 24 Jun 1996Publisher:WileyJournal:FEBS Letters, volume 389, pages 70-74 (issn: 0014-5793, eissn: 1873-3468,

Authors: Johannes Lechner; Jennifer Ortiz;

doi: 10.1016/0014-5793(96)00563-7

pmid: 8682209

The Saccharomyces cerevisiae kinetochore

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Abstract

Accurate chromosome segregation is DApenDAnt on a specialized chromosomal structure, the kinetochore/centromere. The only essential constituent of the S. cerevisiae kinetochore established today is CBF3, a multisubunit complex that binds to S. cerevisiae centromere DNA. Therefore CBF3 and its four components, Cbf3a, Cbf3b, Cbf3c and Cbf3d, will form the centerpiece of this review. In addition, we will DAscribe proteins that are putatively involved in kinetochore function specifically in the context with CBF3 interaction. Furthermore, we discuss the role of the S. cerevisiae kinetochores in a putative cell cycle checkpoint control and in microtubule attachment.

Related Organizations

University of Regensburg
Germany

Keywords

Saccharomyces cerevisiae Proteins, Base Sequence, CBF3, Centromere, Molecular Sequence Data, Nuclear Proteins, Saccharomyces cerevisiae, Microtubules, DNA-Binding Proteins, Fungal Proteins, Kinetochore, Humans, Kinetochores

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7 Research products, page 1 of 1

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