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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao European Journal of ...arrow_drop_down
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European Journal of Pharmacology
Article . 1988 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
European Journal of Pharmacology
Article . 1989
Data sources: Europe PubMed Central
European Journal of Pharmacology
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The endegenous muscarinic acetylcholine receptor in Xenopus oocytes is of the M3 subtype

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1988 English Publisher:Elsevier BVJournal:European Journal of Pharmacology, volume 151, pages 497-500 (issn: 0014-2999, Copyright policy )
Authors: Lambertus A.C.M. Van Wezenbeek; Gé S.F. Ruigt; Jeroen A.D.M. Tonnaer;

doi: 10.1016/0014-2999(88)90551-1

pmid: 3215274

The endegenous muscarinic acetylcholine receptor in Xenopus oocytes is of the M3 subtype

Abstract

The muscarinic acetylcholine receptor of the Xenopus oocyte was characterized electrophysiologically. Iontophoretic responses to acetylcholine were inhibited by the muscarinic antagonists 4-DAMP, pirenzepine and AF-DX 116 at respective IC50 values of 7 nM, 15 microM and 2 microM. This antagonist sensitivity order indicates that the receptor is of the M3 muscarinic subtype.

Related Organizations
Keywords

Xenopus laevis, Piperidines, Oocytes, Animals, Female, Receptors, Cholinergic, Pirenzepine, In Vitro Techniques, Acetylcholine, Membrane Potentials

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 15
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
15
Average
Average
Top 10%
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