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The biosynthesis of glucosamine

Name: The biosynthesis of glucosamine
Keywords: Los Trabajos de Leloir, Los Trabajos del Instituto, Glucosamine, Neurospora, Cardini, Carlos E., Publicaciones, Instituto de Investigaciones Bioquímicas Fundación Campomar ahora Fundación Instituto Leloir, https://purl.org/becyt/ford/1.6, Artículos Científicos, Leloir, Luis F.

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1953 Argentina Publisher:Elsevier BVJournal:Biochimica et Biophysica Acta, volume 12, pages 15-22 (issn: 0006-3002,

Authors: Leloir, Luis Federico; Cardini, Carlos E.;

doi: 10.1016/0006-3002(53)90119-x

pmid: 13115409

handle: 11336/140740

The biosynthesis of glucosamine

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Abstract

Abstract A partially purified enzyme has been prepared from Neurospora crassa which catalyzes the formation of glucosamine phosphate from hexose-6-phosphate and glutamine. The glucosamine phosphate was identified by colour reactions, by dephosphorylation and paper chromatography and by its behaviour towards an acetylating system. Quantitative analysis of amide nitrogen, glutamate, and hexosamine agreed with the following equation: Hexose-6-phosphate + glutamine → glucosamine-6-phosphate + glutamate Crude Neurospora extracts were found to phosphorylate glucosamine in the presence of ATP and, when suitably supplemented, to acetylate glucosamine or glucosamine phosphate.

Country

Argentina

Related Organizations

National Scientific and Technical Research Council
Argentina

Keywords

Los Trabajos de Leloir, Los Trabajos del Instituto, Glucosamine, Neurospora, Cardini, Carlos E., Publicaciones, Instituto de Investigaciones Bioquímicas Fundación Campomar ahora Fundación Instituto Leloir, https://purl.org/becyt/ford/1.6, Artículos Científicos, Leloir, Luis F., https://purl.org/becyt/ford/1, Leloir Investigador

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	233
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 0.1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 1%