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Biochemical and Biophysical Research Communications
Article . 1976 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
Biochemical and Biophysical Research Communications
Article . 1976
Data sources: Europe PubMed Central
Biochemical and Biophysical Research Communications
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The distribution of albumin precursor protein and albumin in liver

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1976Publisher:Elsevier BVJournal:Biochemical and Biophysical Research Communications, volume 72, pages 310-318 (issn: 0006-291X, Copyright policy )
Authors: Kaylene Edwards; Sidney Fleischer; Becca Fleischer; Heide Dryburgh; Gerhard Schreiber;

doi: 10.1016/0006-291x(76)90995-5

pmid: 985474

The distribution of albumin precursor protein and albumin in liver

Abstract

Abstract Two different proteins precipitable with antiserum to albumin exist in liver. One is albumin, the other is precursor albumin. Liver cells in suspension contain mainly precursor, but secrete only albumin. In subcellular fractions isolated from liver homogenate, 95.3% of anti-albumin precipitable protein in the rough endoplasmic reticulum, 51.4% in the smooth endoplasmic reticulum, 33.5% in the Golgi apparatus and 0% in the supernatant fraction was precursor albumin. The results suggest that albumin precursor is synthesized in the rough endoplasmic reticulum and converted into albumin in the smooth endoplasmic reticulum and the Golgi apparatus.

Related Organizations
Keywords

Cytosol, Liver, Animals, Golgi Apparatus, Prealbumin, Endoplasmic Reticulum, Cells, Cultured, Serum Albumin, Rats, Subcellular Fractions

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 52
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
52
Average
Top 10%
Top 10%
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