<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Fatty acyl-acyl carrier protein and fatty acyl-CoA as acyl donors in the biosynthesis of phosphatidic acid in Clostridium butyricum

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1971 English Publisher:Elsevier BVJournal:Biochemical and Biophysical Research Communications, volume 45, pages 1,127-1,133 (issn: 0006-291X,

Authors: Howard Goldfine; Gérard Ailhaud;

doi: 10.1016/0006-291x(71)90136-7

pmid: 5135502

Fatty acyl-acyl carrier protein and fatty acyl-CoA as acyl donors in the biosynthesis of phosphatidic acid in Clostridium butyricum

- Summary
- Subjects
- Related research
  (2)
- Metrics

Abstract

Abstract In the synthesis of phosphatidic acid catalyzed by a particulate fraction from Clostridium butyricum in the presence of fatty acyl derivatives of an acyl carrier protein (ACP) and sn -glycero-3-phosphate, the first acylation of glycero-3-P is more rapid with an unsaturated acyl-ACP than with a saturated acyl-ACP. In the phosphatidic acid formed, carbon-1 is preferentially acylated with an unsaturated fatty acid and carbon-2 with a saturated fatty acid, as they are in the cellular phospholipids. Acylation by the saturated fatty acid at C2 is not very specific for the acyl carrier: palmityl-CoA competes effectively with palmityl-ACP.

Related Organizations

University of Pennsylvania
United States
Centre national de la recherche scientifique
France

Keywords

Clostridium, Carbon Isotopes, Acylation, Fatty Acids, Oleic Acids, Palmitic Acids, Tritium, Bacterial Proteins, Glycerophosphates, Coenzyme A, Carrier Proteins, Phospholipids, Protein Binding

2 Research products, page of 1

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	24
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average

Found an issue? Give us feedback

Average

Top 10%

Average

Fields of Science (3) View all

medical and health sciences

basic medicine

Fields of Science

medical and health sciences

basic medicine

View all

Upload OA version

Are you the author? Do you have the OA version of this publication?

uploadUpload now!