Evidence of a phosphorylated intermediate in mitochondrial oxidative phosphorylation
Copyright policy )Evidence of a phosphorylated intermediate in mitochondrial oxidative phosphorylation
Abstract The effects of aurovertin and oligomycin on the rates of oxidative phosphorylation and arsenate-stimulated respiration have been studied over a wide range of concentrations. It has been found that both arsenate and phosphate can react with an energy-rich intermediate of oxidative phosphorylation even when reaction with ADP is prevented by aurovertin. These results suggest that tenable hypotheses of oxidative phosphorylation should include a phosphorylated intermediate.
- Yale University United States
- University of New Haven United States
Time Factors, Adenine Nucleotides, Antimetabolites, Uncoupling Agents, Mitochondria, Liver, Oxidative Phosphorylation, Stimulation, Chemical, Anti-Bacterial Agents, Arsenic, Phosphates, Rats, Electron Transport, Oxygen Consumption, Depression, Chemical, Animals, Oligomycins
Time Factors, Adenine Nucleotides, Antimetabolites, Uncoupling Agents, Mitochondria, Liver, Oxidative Phosphorylation, Stimulation, Chemical, Anti-Bacterial Agents, Arsenic, Phosphates, Rats, Electron Transport, Oxygen Consumption, Depression, Chemical, Animals, Oligomycins
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