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DNA replication by phage T4 rII mutants without polynucleotide ligase (gene 30)

Name: DNA replication by phage T4 rII mutants without polynucleotide ligase (gene 30)
Creator: J.D. Karam
Keywords: DNA Replication, Virus Cultivation, Polynucleotides, Tritium, Virus Replication, Coliphages, 3. Good health, Ligases, Genes, Species Specificity

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1969 English Publisher:Elsevier BVJournal:Biochemical and Biophysical Research Communications, volume 37, pages 416-422 (issn: 0006-291X,

Authors: J.D. Karam;

doi: 10.1016/0006-291x(69)90931-0

pmid: 4900136

DNA replication by phage T4 rII mutants without polynucleotide ligase (gene 30)

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Abstract

Abstract In phage T4-infected E. coli , the polynucleotide ligase coded for by T4 gene 30 is not required for DNA replication and phage production when the infecting phage is an rII mutant. The wild-type T4 rII gene product may be a nuclease or control a nuclease activity.

Related Organizations

Kettering University
United States

Keywords

DNA Replication, Virus Cultivation, Polynucleotides, Tritium, Virus Replication, Coliphages, Ligases, Genes, Species Specificity, Genetic Code, Mutation, Escherichia coli, Crosses, Genetic, Thymidine

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