descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1977 English Publisher:Elsevier BVJournal:Biochimica et Biophysica Acta (BBA) - Biomembranes, volume 464, pages 459-462 (issn: 0005-2736,

Authors: C. H. Tan; N.A. Peterson; E. Raghupathy;

doi: 10.1016/0005-2736(77)90020-7

pmid: 831805

d-glucosamine uptake by rat brain synaptosomes

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Abstract

Abstract Uptake of d -glucosamine by rat brain synaptosomes occurs via a saturable transport process ( K m 2.1 mM , V 3.0 nmol/mg per min) which was clearly distinguishable from simple diffusion. This transport process is highly sensitive to cytochalasin ( K i = 7 · 10 −5 mM. d -Glucose competitively inhibits d -glucosamine uptake with a K i value of 8 · 10 −1 mM.

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Keywords

Glucosamine, Cytochalasin B, Biological Transport, Active, Brain, Biological Transport, Rats, Diffusion, Kinetics, Glucose, Animals, Synaptosomes

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