descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1980 English Publisher:Elsevier BVJournal:Archives of Oral Biology, volume 25, pages 437-443 (issn: 0003-9969,

Authors: J B, Alves; C R, Machado;

doi: 10.1016/0003-9969(80)90049-7

pmid: 6779785

Histological and histoquantitative study of the rat submandibular gland in chagas disease

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Abstract

Abstract The submandibular glands of young rats killed at intervals after inoculation with the Y strain of Trypanosoma cruzi showed accelerated acinar development together with retarded duct-system maturation particularly in developing granular ducts. Acinar hypertrophy was evident 18 days after inoculation (acute phase); impairment of duct development was found up to 60 days after infection. No histologic or quantitative changes were found in glands of animals killed 97 days or 10–12 months after inoculation (chronic phase).

Related Organizations

Universidade Federal de Minas Gerais
Brazil
UNIVERSIDADE DE SAO PAULO
Brazil

Keywords

Male, Time Factors, Submandibular Gland, Animals, Chagas Disease, Female, Organ Size, Rats

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