<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Immunoglobulins of sheep

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1969 English Publisher:Elsevier BVJournal:Archives of Biochemistry and Biophysics, volume 131, pages 9-17 (issn: 0003-9861,

Authors: Leslie G. Clark; Ralph Heimer; Paul H. Maurer;

doi: 10.1016/0003-9861(69)90100-3

pmid: 4181129

Immunoglobulins of sheep

- Summary
- Subjects
- Metrics

Abstract

Abstract Immunoelectrophoretic analysis of fractions obtained by DEAE-Sephadex ion exchange chromatography suggests that ovine immunoglobulins may comprise at least five distinct classes. In addition to the electrophoretically slow γ2 and fast γ1 immunoglobulin G, there exists another closely related immunoglobulin which may be either another immunoglobulin G or an analog of human immunoglobulin D. Immunoglobulin M and a fraction containing mainly immunoglobulin A have also been prepared. Antibody activity against dinitrophenyl-bovine serum albumin and a heteropolymer composed of glutamic acid, alanine, and tyrosine was found in the slow and fast immunoglobulin G fractions. The slow and the fast immunoglobulin G preparations were also degraded by papain. Analyses made on the recovered breakdown products suggest their close resemblance to similarly prepared fragments of immunoglobulin of man, rabbit, and other mammals.

Keywords

Immunodiffusion, Chemical Phenomena, Protein Hydrolysates, Immune Sera, Carbohydrates, Serum Albumin, Bovine, Chromatography, Ion Exchange, Molecular Weight, Chemistry, Immunoglobulin M, Immunoglobulin G, Papain, Animals, Humans, Cattle, Rabbits, Antigens, Peptides, Immunoelectrophoresis, Dinitrophenols

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	42
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%