
The stable coronary artery disease (SCAD) population is a heterogeneous group of patients both for clinical presentations and for different underlying mechanisms. The recent European Society of Cardiology guidelines extensively review SCAD from its definition to patients' diagnostic and therapeutic management. In this review, we deal with five topics that, in our opinion, represent the most intriguing, novel and/or clinically relevant aspects of this complex coronary condition. Firstly, we deal with a peculiar SCAD population: patients with angina and 'normal' coronary arteries. Secondly, we reinforce the clinical importance of a diagnostic approach based on the pretest probability of disease. Thirdly, we review and critically discuss the novel pharmacological therapies for SCAD patients. Finally, we analyse the results of the most recent clinical trials comparing revascularization versus optimal medical therapy in SCAD patients and review the currently recommended use of intracoronary functional evaluation of stenosis.
Vasodilator Agents, Coronary Vasospasm, Coronary Artery Disease, Piperazines, Microvascular angina, Percutaneous Coronary Intervention, Ranolazine, Humans, Ivabradine, Pretest probabilityof the disease, Angina, Stable, Coronary Artery Bypass, Fractional flow reserve, Nitrates, Benzazepines, Vasospastic angina, Optical medical therapy, Nicorandil, Microvessels, Exercise Test, Stable coronary artery disease, Acetanilides, Smoking Cessation, EMC COEUR-09, Echocardiography, Stress
Vasodilator Agents, Coronary Vasospasm, Coronary Artery Disease, Piperazines, Microvascular angina, Percutaneous Coronary Intervention, Ranolazine, Humans, Ivabradine, Pretest probabilityof the disease, Angina, Stable, Coronary Artery Bypass, Fractional flow reserve, Nitrates, Benzazepines, Vasospastic angina, Optical medical therapy, Nicorandil, Microvessels, Exercise Test, Stable coronary artery disease, Acetanilides, Smoking Cessation, EMC COEUR-09, Echocardiography, Stress
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