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pmid: 25104452
Aortic aneurysms are common and life threatening problems with high rates of death. The initiation and progression of aneurysms are characterized by extensive extracellular matrix degradation and immune cells invasion within arterial wall. During the pathogenesis of all aneurysms, inflammation and immune cells play a significant role. Although T cells are abundant in aneurysm tissue, their functions in initiation and propagation of aneurysms remain unclear. This review summarizes the current state of knowledge of T lymphocytes on this disease and focuses on potential mechanisms of specific T cell responses.
Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Environmental Science(all), T-Lymphocyte Subsets, T-Lymphocytes, Humans, Aortic Aneurysm, Extracellular Matrix
Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Environmental Science(all), T-Lymphocyte Subsets, T-Lymphocytes, Humans, Aortic Aneurysm, Extracellular Matrix
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 9 | |
popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Top 10% | |
influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |