In this paper, using the local coordinate moving frame approach, we investigate bifurcations of generic heteroclinic loop with a hyperbolic equilibrium and a nonhyperbolic equilibrium which undergoes a pitchfork bifurcation. Under some generic hypotheses, the existence of homoclinic loop, heteroclinic loop, periodic orbit and three or four heteroclinic orbits is obtained. In addition, the non-coexistence conditions for homoclinic loop and periodic orbit are also given. Note that the results achieved here can be extended to higher dimensional systems.