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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao International Ophtha...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
International Ophthalmology
Article . 2024 . Peer-reviewed
License: Springer Nature TDM
Data sources: Crossref
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Evaluation of optical coherence tomography and optical coherence tomography angiography findings of fibromyalgia

Authors: Tuğba Aydoğan, Gezginaslan; Utku, Limon; Özlem, Kaleoğlu; Işılay Özsoy, Saygın; Erdinç, Bozkurt; Betül İlkay Sezgin, Akçay;

Evaluation of optical coherence tomography and optical coherence tomography angiography findings of fibromyalgia

Abstract

To execute comprehensive study about optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) findings in fibromyalgia (FM) to elaborate macula, optic disk changes.A total of 84 participants comprising 44 FM patients and 40 healthy controls were included. Macular full thickness, retinal nerve fiber layer (RNFL), ganglion cell layer (GCL)+, GCL++, superficial vessel density (SVD), deep vessel density (DVD), foveal avascular zone (FAZ), circumpapillary vessel density (cpVD), RNFL measurements were evaluated using OCT/OCTA. Each FM patient completed Fibromyalgia Impact Questionnaire (FIQ), Short Form-36 (SF-36), Widespread Pain Index (WPI), Symptom Severity Scale (SSS). OCT/OCTA parameters were compared between controls and FM patients. Correlation between FIQ, SF-36, WPI, SSS and OCT/OCTA were evaluated. Logistic regression analysis were performed to analyze associated parameters.Macular full thickness parafoveal nasal, temporal, superior, inferior, perifoveal temporal, superior, GCL+ parafoveal nasal, temporal, superior, inferior, GCL+ perifoveal temporal, GCL++ parafoveal nasal, temporal, superior, inferior, GCL++ perifoveal nasal were lower in FM patients. Difference was not found in SVD, DVD or FAZ measurements. cpVD in nasal, superior, inferior were higher in FM patients. RNFL temporal was lower in FM patients. Weak correlations were observed between FIQ, SF-36, WPI, SSS scores and OCT/OCTA parameters. Superior cpVD was associated with FM due to logistic regression analysis.OCT/OCTA can provide objective supplementary measurements in the assessment of FM. Changes in measurements like RNFL, macula GCL, cpVD are important to evaluate the neuroretinal changes in FM.

Keywords

Male, Adult, Retinal Ganglion Cells, Fibromyalgia, Fundus Oculi, Optic Disk, Visual Acuity, Retinal Vessels, Middle Aged, Nerve Fibers, Cross-Sectional Studies, Retinal Diseases, Humans, Female, Macula Lutea, Fluorescein Angiography, Tomography, Optical Coherence

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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