Highly divergent cattle hepacivirus N in Southern Brazil
Copyright policy )Highly divergent cattle hepacivirus N in Southern Brazil
The genus Hepacivirus includes 14 species (Hepacivirus A-N). In this study, we determined a partial genome sequence of a highly divergent bovine hepacivirus (hepacivirus N, HNV) isolate from cattle in Southern Brazil. Previously described HNV isolates have shared 80-99.7% nucleotide sequence identity in the NS3 coding region. However, the sequence determined in this study had 72.6% to 73.8% nucleotide sequence identity to known HNV NS3 sequences. This high divergence could be seen in a phylogenetic tree, suggesting that it represents a new genotype of HNV. These data expand our knowledge concerning the genetic variability and evolution of hepaciviruses.
Evolution, Molecular, Animals, Cattle Diseases, Genetic Variation, Cattle, Genome, Viral, Hepacivirus, Hepatitis C, Brazil, Phylogeny
Evolution, Molecular, Animals, Cattle Diseases, Genetic Variation, Cattle, Genome, Viral, Hepacivirus, Hepatitis C, Brazil, Phylogeny
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