A child with a t(11;19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1998Publisher:Springer Science and Business Media LLCJournal:Virchows Archiv, volume 433, pages 579-581 (issn: 0945-6317, eissn: 1432-2307,

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Authors: G, Stenman; V, Petursdottir; G, Mellgren; J, Mark;

doi: 10.1007/s004280050293

pmid: 9870694

A child with a t(11;19)(q14-21;p12) in a pulmonary mucoepidermoid carcinoma

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Abstract

We report on a mucoepidermoid carcinoma (MEC) of the lung in a 6-year-old girl with a t(11;19)(q14-21;p12) as the sole karyotypic abnormality. An apparently identical t(11;19) has been reported previously in a MEC originating from the major and minor salivary glands. Our findings indicate that the t(11;19) is intimately associated with the mucoepidermoid phenotype and may be used as a diagnostic marker for this tumour type.

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Keywords

Lung Neoplasms, Chromosomes, Human, Pair 11, Immunohistochemistry, Translocation, Genetic, Karyotyping, Biomarkers, Tumor, Humans, Carcinoma, Mucoepidermoid, Female, Child, Chromosomes, Human, Pair 19

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