TLR2 in murine atherosclerosis

descriptionPublicationkeyboard_double_arrow_right Article 06 Dec 2007 English Publisher:Springer Science and Business Media LLCJournal:Seminars in Immunopathology, volume 30, pages 23-27 (issn: 1863-2297, eissn: 1863-2300,

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Authors: Peter S, Tobias; Linda K, Curtiss;

doi: 10.1007/s00281-007-0102-3

pmid: 18058099

TLR2 in murine atherosclerosis

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Abstract

Atherosclerosis was once thought to be solely a disease of lipid accumulation in the vessel wall. It does involve lipid accumulation, but inflammation appears to be an important driving factor. Consequently, our laboratory undertook to examine the role(s) of TLRs, and especially TLR2, in murine models of atherosclerosis.

Related Organizations

Scripps Research Institute
United States

Keywords

Inflammation, Mice, Knockout, Toll-Like Receptor 4, Disease Models, Animal, Mice, Animals, Endothelial Cells, Atherosclerosis, Toll-Like Receptor 2, Signal Transduction

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