Malignancy in pigmented villonodular synovitis
Copyright policy )Malignancy in pigmented villonodular synovitis
Malignant pigmented villonodular synovitis is an extremely rare and controversial disease. We describe malignant change in pigmented villonodular synovitis of the ankle in a patient with an unusually long clinical history. Symptoms began at age 21, metastatic disease developed at age 85, and the patient died 1 year later. The histologic appearance of the malignant tumor differed from that in most reported cases, in that spindle-shaped cells predominated. Lymph node metastasis also developed, a feature uncommon to soft tissue sarcomas.
- Mayo Clinic United States
Adult, Lung Neoplasms, Time Factors, Tibia, Bone Neoplasms, Synovitis, Pigmented Villonodular, Radiography, Cell Transformation, Neoplastic, Fatal Outcome, Lymphatic Metastasis, Humans, Female, Ankle Joint
Adult, Lung Neoplasms, Time Factors, Tibia, Bone Neoplasms, Synovitis, Pigmented Villonodular, Radiography, Cell Transformation, Neoplastic, Fatal Outcome, Lymphatic Metastasis, Humans, Female, Ankle Joint
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