
pmid: 11201036
We report an osteoblastoma-like osteosarcoma in the right proximal fibula in a 22-year-old woman. Radiographs showed an irregular osteolytic lesion from the metaphysis to the epiphysis in the proximal fibula with partial destruction of cortical bone. Tissue from a biopsy indicated a typical osteoblastoma. Curettage and bone graft was performed. One year after the surgery, local recurrence occurred, and a wide excision was performed. Histological examination of the en-bloc surgical specimen revealed the tumor had permeated through the host bony trabeculae, although the nuclear atypia was not marked. Immunohistochemical expression of MIB-1 was detected in 9.0% of cells.
Adult, Osteosarcoma, Biopsy, Nuclear Proteins, Antigens, Nuclear, Bone Neoplasms, Magnetic Resonance Imaging, Ki-67 Antigen, Fibula, Humans, Female, Neoplasm Invasiveness, Osteoblastoma, Neoplasm Recurrence, Local
Adult, Osteosarcoma, Biopsy, Nuclear Proteins, Antigens, Nuclear, Bone Neoplasms, Magnetic Resonance Imaging, Ki-67 Antigen, Fibula, Humans, Female, Neoplasm Invasiveness, Osteoblastoma, Neoplasm Recurrence, Local
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