We would like to invite you to participate in the Analytical Challenge, a series of puzzles to entertain and challenge our readers. This special feature of “Analytical and Bioanalytical Chemistry” (ABC) has established itself as a truly unique quiz series, with a new scientific puzzle published every three months. Readers can access the complete collection of published problems with their solutions on the ABC homepage at http://www.springer.com/abc. Test your knowledge and tease your wits in diverse areas of analytical and bioanalytical chemistry by viewing this collection. In the present challenge, measurement uncertainty is the topic. And please note that there is a prize to be won (a Springer book of your choice up to a value of €100). Please read on…