Death by parenteral nutrition
Copyright policy )Death by parenteral nutrition
According to the Merriam-Webster Dictionary a poison or toxin is “a substance that through its chemical action usually kills, injures or impairs an organism” [1]. Based on this definition, in the critically ill, total parenteral nutrition (TPN) meets all the criteria of a poison/toxin. Furthermore, TPN exhibits other properties common to many toxins, namely, the presence of a dose response curve (the more you give the greater the toxicity), its toxicity is most evident in those with depressed host defense mechanisms (the critically ill) and an antidote exists (enteral nutrition).
- University of Pittsburgh United States
- University of Pittsburgh Medical Center United States
Enteral Nutrition, Evidence-Based Medicine, Treatment Outcome, Critical Care, Critical Illness, Patient Selection, Immune Tolerance, Humans, Parenteral Nutrition, Total, Morbidity
Enteral Nutrition, Evidence-Based Medicine, Treatment Outcome, Critical Care, Critical Illness, Patient Selection, Immune Tolerance, Humans, Parenteral Nutrition, Total, Morbidity
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