This paper deals with experimental work to improve the settling and filtration characteristics of an industrial sludge from an iron-ore mine using synthetic polymeric flocculants. The experimental work consisted of the characterization and evaluation of suitable flocculants to enhance settling and filtration rates. The optimum dosage of the flocculants were determined. The experimental results revealed that the settling rate can he increased many times, compared to untreated sludge, by using a suitable combination of flocculants. Compared to cationic and nonionic flocculants, anionic flocculants were found to be more efficient in sludge flocculation. The synergistic effect of two anionic flocculants produced the best settling conditions. Filtration test results also reveal that suitable flocculants can improve the dewatering characteristics of the slurry.