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Article . 1991
Full-Text: https://orbi.uliege.be/bitstream/2268/185213/1/Gaignage.EurJDrugMetabolismPharmacokinetics.1991.pdf
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European Journal of Drug Metabolism and Pharmacokinetics
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European Journal of Drug Metabolism and Pharmacokinetics
Article . 1991 . Peer-reviewed
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European Journal of Drug Metabolism and Pharmacokinetics
Article . 1992
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https://dx.doi.org/10.1007/bf0...
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Article . 1991 . Peer-reviewed
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Dexamethasone bovine pharmacokinetics

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1991 Belgium English Publisher:Springer Science and Business Media LLCJournal:European Journal of Drug Metabolism and Pharmacokinetics, volume 16, pages 219-221 (issn: 0378-7966, eissn: 2107-0180, Copyright policy )
Authors: Gaignage, Ph; Lognay, Georges C.; Bosson, Danièle; Vertongen, D.; Dreze, Ph; Marlier, Michel; Severin, Michel;

doi: 10.1007/bf03189963

pmid: 1814739

handle: 2268/185213 , 2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/218800

Dexamethasone bovine pharmacokinetics

Abstract

Dexamethasone phosphate (DXM-PHO) is an ester which is quickly hydrolysed by the bovine and the dexamethasone (DXM) plasma half-life was 5.16 h. It has been demonstrated that 54 h after DXM-PHO injection, DXM concentrations were lower than 0.1 mg/ml. Tritiated dexamethasone was also administered twice to an another young bull for metabolite investigation. The elapsed time required to recover, in plasma, half of the radioactivity injected was 8.8 h. Radioactivity recovery in the urine reached 36.4% and 22.6% for the first and the second injections respectively.

Country
Belgium
Related Organizations
Keywords

Male, half-life, bovine, Hydrolysis, Pharmacologie, Agriculture & agronomy, Life sciences, Injections, Intramuscular, urine, Dexamethasone, Agriculture & agronomie, Injections, Intravenous, Sciences du vivant, Animals, Regression Analysis, Cattle, plasma, Half-Life

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 13
    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
13
Average
Top 10%
Average
Green
bronze