Droplets of Zr41Ti14Cu12.5Ni10Be22.5 glass forming alloys with different sizes are solidified in a drop tube containerless processing. Glass transition behavior, crystallization kinetics, and the phase evolution during annealing of the Zr41Ti14Cu12.5Ni10Be22.5 glassy spheres are investigated. The experimental results indicate that the apparent activation energy of the glass transition (Eg = 435.5 kJ/mol), and the activation energy of the main crystallization reaction (E p1= 249.6 kJ/mol) are obviously different from those of bulk glass samples prepared by water quenched (Eg=559.1 kJ/mol and Ep1 =192.5 kJ/mol). The difference is discussed in the view point of the atomic configuration of the liquid state of the metallic glass and nucleation mechanism.