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Tau in neurodegenerative diseases: Tau phosphorylation and assembly

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2004 Spain English Publisher:Springer Science and Business Media LLCJournal:Neurotoxicity Research, volume 6, pages 477-482 (issn: 1029-8428, eissn: 1476-3524,

Authors: Ávila, Jesús; Pérez, Mar; Lim, Filip; Gómez Ramos, Alberto; Hernández, Félix; Lucas, José Javier;

doi: 10.1007/bf03033284

pmid: 15639780

handle: 10261/251581

Tau in neurodegenerative diseases: Tau phosphorylation and assembly

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Abstract

The possible link between tau phosphorylation and tau assembly in these neurodegenerative diseases known as tauopathies is described. Additionally, this link is supported by an in vitro experiment showing the higher capacity of phosphotau to assemble in some specific conditions; and, by a recently reported experiment using a tau transgenic mouse model.

Country

Spain

Related Organizations

Autonomous University of Madrid
Spain
Spanish National Research Council
Spain
Centro de Biología Molecular Severo Ochoa
Spain

Keywords

Mice, Animals, Humans, Mice, Transgenic, Neurodegenerative Diseases, tau Proteins, Phosphorylation, Cell Line

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	46
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%