From a study of forty-one cases of atrophic gastritis and smaller groups of patients with pernicious anemia, psychoneurosis, peptic ulcer, cholelithiasis, and the other types of gastritis, we may draw the following conclusions: 1. The digestive symptoms of atrophic gastritis are rather indefinite; the general symptoms are more characteristic, although an accurate diagnosis is possible only by gastroscopic examination. 2. The syndrome of epigastric discomfort (such as fullness, belching, heaviness and pain) and poor appetite, distressing weakness, fatigue, “inexplicable” nervousness, sore tongue, numbness and tingling of the extremities is highly suggestive of atrophic gastritis. 3. Atrophic gastritis should be regarded as a serious disease.