Fentanyl-oxygen anaesthesia for coronary artery surgery: cardiovascular and antidiuretic hormone responses

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1979 English Publisher:Springer Science and Business Media LLCJournal:Canadian Anaesthetists’ Society Journal, volume 26, pages 168-172 (issn: 0008-2856, eissn: 1496-8975,

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Authors: T H, Stanley; D M, Philbin; C H, Coggins;

doi: 10.1007/bf03006976

pmid: 380788

Fentanyl-oxygen anaesthesia for coronary artery surgery: cardiovascular and antidiuretic hormone responses

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Abstract

This study demonstrates that large doses of fentanyl, as the sole anaesthetic with ventilation with oxygen, produces complete anaesthesia and minimal changes in cardiovasuclar dynamics in patients with coronary artery disease. It also indicates that high dose fentanyl anaesthesia blocks the increase in plasma anti-diuretic hormone and cardiovascular dynamics which are so common with morphine and other anaesthetic techniques during tracheal intubation and surgical stimulation in patients with coronary artery disease. Our findings suggest that fentanyl-oxygen anaesthesia is an attractive technique in patients with coronary artery disease.

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Keywords

Clinical Trials as Topic, Vasopressins, Hemodynamics, Blood Pressure, Stroke Volume, Coronary Vessels, Fentanyl, Oxygen, Heart Rate, Anesthesia, Intravenous, Humans, Vascular Resistance, Cardiac Output

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