Butyrylcholinesterase inhibitory guaianolides fromAmberboa ramosa
Copyright policy )Butyrylcholinesterase inhibitory guaianolides fromAmberboa ramosa
Phytochemical investigation of the whole plant of Amberboa ramosa led to the isolation of six sesquiterpene lactones which could be identified as 8alpha-hydroxy-11beta-methyl-1alphaH, 5alphaH, 6betaH, 7alphaH, 11alphaH-guai-10(14), 4(15)-dien-6, 12-olide(1), 3beta, 8alpha-dihydroxy-11alpha-methyl-1alphaH, 5alphaH, 6betaH, 7alphaH, 11betaH-guai-10(14), 4 (15)-dien-6, 12-olide (2), 3beta, 4alpha, 8alpha-trihydroxy-4beta-(hydroxymethyl)-1alphaH, 5alphaH, 6betaH, 7alphaH-guai-10(14), 11(13)-dien-6, 12-olide (3), 3beta, 4alpha, 8alpha-trihydroxy-4beta-(chloromethyl)-1alphaH, 5alphaH, 6betaH, 7alphaH-guai-10(14),11(13)-dien-6, 12-olide(4), 3beta, 4alpha, dihydroxy-4beta-(hydroxymethyl)-1alphaH, 5alphaH, 6betaH, 7alphaH-guai-10(14),11(13)-dien-6, 12-olide(5), 3beta, 4alpha-dihydroxy-4beta-(chloromethyl)-8alpha-(4-hydroxymethacrylate)-1alphaH, 5alphaH, 6betaH, 7alphaH-guai-10(14),11 (13)-dien-6,12-olide (6) by spectroscopic methods. All of them showed inhibitory potential against butyrylcholinesterase.
Spectrometry, Mass, Electrospray Ionization, Spectrophotometry, Infrared, Galantamine, Asteraceae, Spectrometry, Mass, Fast Atom Bombardment, Kinetics, Sesquiterpenes, Guaiane, Butyrylcholinesterase, Cholinesterase Inhibitors
Spectrometry, Mass, Electrospray Ionization, Spectrophotometry, Infrared, Galantamine, Asteraceae, Spectrometry, Mass, Fast Atom Bombardment, Kinetics, Sesquiterpenes, Guaiane, Butyrylcholinesterase, Cholinesterase Inhibitors
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