Osteomalacia in ureterosigmoidostomy

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1969 English Publisher:Springer Science and Business Media LLCJournal:Irish Journal of Medical Science, volume 2, pages 523-530 (eissn: 0021-1265,

Copyright policy )Publicly funded

Authors: J F, Donohoe; R, Freaney; F P, Muldowney;

doi: 10.1007/bf02955462

pmid: 5370505

Osteomalacia in ureterosigmoidostomy

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Abstract

(1) A case of severe osteomalacia with chronic metabolic acidosis following ureterosigmoidostomy is described. (2) Treatment with alkali reversed the acidosis and induced positive phosphate balance. Maintenance therapy with alkali alone has been continued for twenty-four months without recurrence of symptoms. (3) The role of acidosis in the production of osteomalacia is discussed and it is postulated that acidosis exerts its effect through phosphate depletion.

Related Organizations

University College Dublin
Ireland
St. Vincent's Health System
United States

Keywords

Male, Bicarbonates, Postoperative Complications, Colon, Sigmoid, Osteomalacia, Humans, Middle Aged, Ureter, Vitamin D, Acidosis, Phosphates

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