Cardiac myxomas may present with a broad range of clinical features. There is a classic triad of features that includes obstructive cardiac signs, embolic signs, and constitutional manifestations. All patients present with one or more symptoms from this triad, but diagnosis may be elusive due to the nonspecific nature of some of these features. Although myxomas are uncommon and benign, the diagnosis must be considered when signs and symptoms suggest it due to the high associated morbidity and mortality. The size, character, location, and mobility of the tumor determine the type and severity of symptoms. Echocardiography is the most important tool used to establish the diagnosis, but CT and MRI may provide additional information in some cases. Prompt surgical resection of the tumor is the appropriate treatment. The overall prognosis is excellent, but patients should be followed due to the risk of recurrence.