Herpes simplex encephalitis and sarcoidosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1979 English Publisher:Springer Science and Business Media LLCJournal:Irish Journal of Medical Science, volume 148, pages 54-57 (issn: 0021-1265, eissn: 1863-4362,

Copyright policy )Publicly funded

Authors: E C, Sweeney; L, McDonnell;

doi: 10.1007/bf02938051

pmid: 478815 , 27517389

Herpes simplex encephalitis and sarcoidosis

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Abstract

Fatal herpes simplex encephalitis occurring in a patient with sarcoidosis is described. Ultrastructural study of brain tissue revealed the presence of herpesvirus particles. The association of these 2 diseases has not been recorded before. The encephalitis in this case probably represents an opportunistic viral infection in the face of depressed cellular immunity. Progressive multifocal leukoencephalopathy, a disease of putative viral aetiology, is known to occur in patients with sarcoidosis and it is suggested that this case represents a similar pathogenetic association.

Related Organizations

Trinity College Dublin
Ireland

Keywords

Adult, Sarcoidosis, Brain, Encephalitis, Humans, Female, Herpes Simplex

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