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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Medical Oncology and...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Medical Oncology and Tumor Pharmacotherapy
Article . 1986 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
Medical Oncology and Tumor Pharmacotherapy
Article . 1987
Data sources: Europe PubMed Central
https://www.ncbi.nlm.nih.gov/p...
Other literature type
Data sources: Microsoft Academic Graph
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Interleukin-2 (IL-2) and its receptor

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Sep 1986 English Publisher:Springer Science and Business Media LLCJournal:Medical Oncology and Tumor Pharmacotherapy, volume 3 (issn: 0736-0118, Copyright policy )
Authors: Eva-Lotta Larsson;

doi: 10.1007/bf02934999

pmid: 3100883

Interleukin-2 (IL-2) and its receptor

Abstract

The interleukin-2 (IL-2) receptor system which is responsible for T-cell cycle progression is a unique hormone-receptor system in that both the ligand and the receptor need to be induced. In the present article I will review the biological and molecular characteristics of IL-2 and its receptor, as well as the differential triggering and growth requirements that L3T4+ (T4+) helper and Lyt-2+ (T8+) cytotoxic/suppressor T-cells display to respond. The various mechanisms of regulation operating to restrain clonal IL-2-dependent expansion of normal T-lymphocytes will be discussed.

Related Organizations
Keywords

Molecular Weight, Gene Expression Regulation, T-Lymphocytes, Humans, Interleukin-2, Receptors, Interleukin-2, Receptors, Immunologic

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 3
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
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