New antimycobacterialS-alkylisothiosemicarbazones

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2005 English Publisher:Springer Science and Business Media LLCJournal:Folia Microbiologica, volume 50 (issn: 0015-5632, eissn: 1874-9356,

Copyright policy )

Authors: K, Waisser; L, Heinisch; M, Slosárek; J, Janota;

doi: 10.1007/bf02931433

pmid: 16681143

New antimycobacterialS-alkylisothiosemicarbazones

- Summary
- Subjects
- Metrics

Abstract

In connection with a systematic study of antimycobacterial agents against potentially pathogenic strains the series of 12 S-alkylisothiosemicarbazones was evaluated for in vitro antimycobacterial activity against Mycobacterium tuberculosis, M. kansasii, M. fortuitum, two strains of M. intracellulare and three strains of M. avium. Quinoline-4-carbaldehyde-S-hexyl-isothiohydrazone was found to be more active against potentially pathogenic strains than isoniazide.

Related Organizations

Leibniz Association
Germany
National Institute of Public Health
Czech Republic
Charles University
Czech Republic
Hans Knöll Institute
Germany

Keywords

Thiosemicarbazones, Aldehydes, Mycobacterium fortuitum, Nontuberculous Mycobacteria, Microbial Sensitivity Tests, Mycobacterium tuberculosis, Mycobacterium avium Complex, Anti-Bacterial Agents, Mycobacterium kansasii, Mycobacterium avium

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	7
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average