Hybrid antibiotics

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2003 English Publisher:Springer Science and Business Media LLCJournal:Folia Microbiologica, volume 48 (issn: 0015-5632, eissn: 1874-9356,

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Authors: V, Bĕhal;

doi: 10.1007/bf02931272

pmid: 12744073

Hybrid antibiotics

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Abstract

Hybrid antibiotics that do not occur in nature have been obtained by combining structural genes of antibiotic producers. Some of these substances were effective against pathogenic microorganisms resistant against antibiotics produced by the parent strains. The majority of hybrid antibiotics were obtained by combining genes encoding polyketide synthases. Hybrid peptides with new biological properties have also been synthesized.

Related Organizations

Czech Academy of Sciences
Czech Republic

Keywords

Recombination, Genetic, Bacteria, Genes, Bacterial, Multienzyme Complexes, Genetic Engineering, Anti-Bacterial Agents

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