
doi: 10.1007/bf02905038
pmid: 6427880
A woman with multicentric reticulohistiocytosis, having symptoms including bleeding and a borderline level of factor VIII, was given an i.v. infusion of DDAVP as a pharmacological test to evaluate the release of factor VIII-related properties from storage sites. The results show a reduced response to DDAVP in the patient in comparison with a normal control subject. This could be due either to a defect in the release of the factor VIII complex after DDAVP or to a reduced synthesis and/or storage capacity by the storage cells.
Arginine Vasopressin, Factor VIII, Adolescent, Humans, Deamino Arginine Vasopressin, Female, Lymphatic Diseases
Arginine Vasopressin, Factor VIII, Adolescent, Humans, Deamino Arginine Vasopressin, Female, Lymphatic Diseases
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