Intermediate filaments in hyaline material in alcoholic liver disease (Mallory bodies) and in cultured hepatoma cells
Copyright policy )Intermediate filaments in hyaline material in alcoholic liver disease (Mallory bodies) and in cultured hepatoma cells
Antibodies specific for cytoskeletal intermediate (10 nm) filaments reacted both with the hyaline deposits in alcoholic liver disease (Mallory bodies) and with perinuclear hyaline material of cultured hepatoma cells used as a model for hyaline formation in vitro. Our results suggest that disorganization and accumulation of intermediate filaments is an important step in the pathogenesis of alcoholic liver injury.
- University of Helsinki Finland
Hyalin, Carcinoma, Hepatocellular, Hepatitis, Alcoholic, Liver Cirrhosis, Alcoholic, Culture Techniques, Liver Neoplasms, Animals, Humans, Liver Diseases, Alcoholic, Rats
Hyalin, Carcinoma, Hepatocellular, Hepatitis, Alcoholic, Liver Cirrhosis, Alcoholic, Culture Techniques, Liver Neoplasms, Animals, Humans, Liver Diseases, Alcoholic, Rats
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