“Clot-begotten bleeding’ is the essence of the syndrome of consumptive coagulopathy. It occurs in a variety of clinical conditions and its recognition may be vital for management of the patient and his ultimate outcome. A high rate of suspicion aided by the laboratory, is the key to early diagnosis. Heparin and fresh blood transfusion are the main basis of therapy. Further work is required to elucidate the pathogenesis and the role of other therapeutic agents.