Tumor cells adhere to intraperitoneal injection sites

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1984 English Publisher:Springer Science and Business Media LLCJournal:Virchows Archiv B Cell Pathology Including Molecular Pathology, volume 45, pages 339-345 (issn: 0042-6431,

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Authors: R, Kühnlein; E A, Friedrich; V, Burkart; R, Süss;

doi: 10.1007/bf02889876

pmid: 6145244

Tumor cells adhere to intraperitoneal injection sites

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Abstract

Tumor cells injected intraperitoneally form cell plaques at injection sites in the abdominal wall of mice within a few minutes. Tumor cells appear to be transported passively and chemotactic factors are not involved. Dihydrocortisol blocks cell adherence and silica particles , assumed to destroy macrophages, abolish cell plaque formation.

Related Organizations

German Cancer Research Center
Germany
Helmholtz Association of German Research Centres
Germany

Keywords

Time Factors, Hydrocortisone, Chemotaxis, Mice, Inbred Strains, Silicon Dioxide, Mice, Neoplasm Seeding, Neoplasms, Cell Adhesion, Animals, Peritoneum

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