Nuclear fibrous lamina in pathological human synovial membrane

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1974 English Publisher:Springer Science and Business Media LLCJournal:Virchows Archiv B Cell Pathology, volume 15, pages 223-228 (issn: 0340-6075,

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Authors: F N, Ghadially; A F, Oryschak; D M, Mitchell;

doi: 10.1007/bf02889339

pmid: 4209845

Nuclear fibrous lamina in pathological human synovial membrane

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Abstract

The synovial membrane from a patient with multiple sclerosis, psoriasis and arthritis was examined with the electron microscope. A nuclear fibrous lamina much thicker than that known to occur in normal cells of vertebrates was found in the synovial intimal cells and in subsynovial fibroblasts of this patient. Since such a thickened lamina has also been found in repair tissue in articular cartilage it is thought that thickening of the lamina may be related to the process of hyperplasia and repair.

Related Organizations

University of Saskatchewan
Canada

Keywords

Arthritis, Rheumatoid, Cartilage, Articular, Multiple Sclerosis, Synovial Membrane, Humans, Psoriasis, Female, Fibroblasts

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