Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression
Copyright policy )Effects of surgical trauma on interleukin 2 production and interleukin 2 receptor expression
To elucidate the mechanism of immunologic abnormalities induced by surgical trauma, we measured interleukin 2 (IL-2) production and IL-2 receptor expression in peripheral blood mononuclear cells from 16 patients with cholelithiasis. Compared with preoperative levels, IL-2 production and IL-2 receptor expression were significantly reduced on postoperative day 4, and the reduction was consistent with the suppression of lymphocyte proliferative response to phytohemagglutinin.
- Centre of Experimental Medicine of the Slovak Academy of Sciences Slovakia
- Wuhan Union Hospital China (People's Republic of)
- Tongji Medical College China (People's Republic of)
Adult, Immunosuppression Therapy, Male, Cholelithiasis, Leukocytes, Mononuclear, Humans, Interleukin-2, Female, Receptors, Interleukin-2, Postoperative Period, Middle Aged, Aged
Adult, Immunosuppression Therapy, Male, Cholelithiasis, Leukocytes, Mononuclear, Humans, Interleukin-2, Female, Receptors, Interleukin-2, Postoperative Period, Middle Aged, Aged
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