Antimicrobially active substances

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1970 English Publisher:Springer Science and Business Media LLCJournal:Folia Microbiologica, volume 15, pages 54-58 (issn: 0015-5632, eissn: 1874-9356,

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Authors: A, Capek; A, Simek; D, Nĕmcová; V, Janata;

doi: 10.1007/bf02867048

pmid: 5411490

Antimicrobially active substances

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Abstract

The antimycotic activity of 41 quaternary ammonium compounds was studied. The spectrum of their effect was evaluated in eight microbial strains. Homologues, isomers or close analogues of Septonex, i.e. α-carbetoxypentadecyl-trimethylammonium bromide (XII) were found to be the most active. The presence of an alicyclic or an aromatic ring or of a pyridine residue inhibited antimycotic activity, while substitution of hydrogen by a halogen potentiated it.

Keywords

Quaternary Ammonium Compounds, Antifungal Agents

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