Kokusaginine: Plant sources and its isolation fromPtelea trifoliata root bark

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1969 English Publisher:Springer Science and Business Media LLCJournal:Economic Botany, volume 23, pages 75-81 (issn: 0013-0001, eissn: 1874-9364,

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Authors: R. K. Mulvey; J. Zalewski;

doi: 10.1007/bf02862974

Kokusaginine: Plant sources and its isolation fromPtelea trifoliata root bark

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Abstract

1. Kokusaginine, as the free base, has been isolated in a yield of 0.015% from root bark ofPtelea trifoliata. 2. By descending paper partition chromatography an Rf value of 0.70 has been determined for the alkaloid. 3. The incorporation of 2% hydrochloric acid solution and hot benzene in the extraction procedure appears to facilitate the isolation of kokusaginine. 4. Members of the Rutaceae are significant natural sources of the alkaloid. 5. Pharmacological testing of kokusaginine is being conducted currently.

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