The present study reports on 130 children, aged 0–5 years, who had acute infective diarrhea.E. coli was the commonest invading organism followed byShigella, Salmonella, Parotyphi B, Klebsiella andStreptococcus faecalis. On serological examination, 18 different serotypes ofE. coli were detected, the commonest being 0128 (12.61% cases). In eight cases, where the recovery took longer than 72 hours, multiple causative organisms were cultured.