One hundred patients suffering from pyogenic meningitis were studied. The majority of the patients were in the 5–12-year-age group and suffered from meningococcal meningitis, Patients under 2 years were more severely ill, as compared to those in the 5–12-year-age group. No correlation of severity of the illness was found with duration of the illness. Complications like peripheral circulatory failure, arthritis, neurological deficit involving chiefly the cranial nerves, sub-dural effusion and herpes simplex were noted. They were treated with multiple antibiotics-penicillin, sulphonamides and chloramphenicol in appropriately high doses. I.V. administration of fluids and chemotherapeutic agents in the first 24 hours were administered to patients. A majority of the patients made an uneventful recovery and only 3% died. Repeat lumbar puncture routinely was not considered to be essential. The low mortality and sequelae rate could well be attributed to the maintenance of fluid balance and intravenous administration of antibiotics. Steroids do not seem to have any role in preventing or combating peripheral circulatory failure.