A woman diagnosed at the age of 15 of a Hodgkin’s disease, mixed cellularity, received thoracic radiotherapy. At the age of 17 was treated again with radiotherapy because of recurrence. At 30 years old, she was treated of a second recurrence with chemotherapy and radiotherapy. After seven years of complete remission, she was diagnosed a breast carcinoma, and a year later it was detected a second contralateral carcinoma, treated both of them with radical surgery and hormonotherapy. The possibility of developing long-term radiation-induced mammary neoplasms in young women previously irradiated for a Hodgkin’s disease is discussed.