Hairy cell leukemia

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2007 English Publisher:Springer Science and Business Media LLCJournal:Medical Oncology, volume 24, pages 7-15 (issn: 1357-0560, eissn: 1559-131X,

Copyright policy )Publicly funded

Authors: Ronan, Swords; Francis, Giles;

doi: 10.1007/bf02685898

pmid: 17673807

Hairy cell leukemia

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Abstract

Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by pancytopenia and variable infiltration of the reticuloendothelial system with "hairy" lymphocytes. HCL is more common in men than women and has a median age of diagnosis of 52 yr. Typically, patients with HCL respond well to purine analog-based therapy. The purpose of this review will be to establish the current status of HCL with respect to its pathophysiology, diagnosis, management, and future directions.

Related Organizations

The University of Texas MD Anderson Cancer Center
United States
University College Hospital
United Kingdom
University of Galway
Ireland
Saolta University Health Care Group
Ireland
The University of Texas at Austin
United States

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Keywords

Leukemia, Hairy Cell, Humans

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