The author’s charge was to discuss recent trends in research and development on precipitation hardened aluminum alloys and to indicate where research is needed. This will be done for three areas: fatigue, properties of grain boundaries and interfaces, and stability of precipitates at elevated temperatures. Present strong precipitation hardened aluminum alloys do not have high endurance limits. One problem is that the small GP zones are cut by the dislocations giving rise to highly localized deformation which aids fatigue crack initiation. A duplex structure with relatively large uniformly spaced precipitates to give more homogeneous deformation plus small precipitates to give high yield strength is a promising approach. The structures of precipitation hardened aluminum base alloys are essentially controlled by the stabilities of the various precipitates and the interfacial energies. Precipitates with high interfacial energies tend to precipitate preferentially at grain boundaries giving embrittlement. Low interfacial energy means easy nucleation, a uniform precipitate distribution, and resistance to coarsening at elevated temperatures. For elevated temperature use, the precipitate must be stable at elevated temperatures. Precipitation hardened aluminum alloys do not have good elevated temperature properties because the hardening precipitates normally used, GP zones, are not stable at elevated temperatures. Thus a low interfacial energy, ductile precipitate, which is stable at elevated temperatures, is needed for aluminum. Possibilities for achieving such precipitates will be discussed.