The effect has been investigated of prior damage on the creep crack propagation characteristics of 0.5 pct Cr, 0.5 pct Mo, 0.25 pct V steel at 823 K. On a macroscopic basis, the parametersK 1 andC * both appear to correlate withda/dt although the parameterC * is unable to distinguish between virgin and damaged specimens. Rupture lives in the predamaged specimens are reduced by up to 60 pct when compared to virgin samples. Microscopically, it is found that the nature of the cavitation damage suggests that surface and grain boundary diffusion processes may have a minimal part to play, crack growth being controlled by the growth of cavities which is in turn controlled by the deformation of the surrounding matrix. A number of microscopic models are compared with the experimental data and it is suggested that a model which gives the best correlation with results is one proposed on the basis of matrix deformation.