High-velocity oxygen fuel (HVOF) thermal-sprayed carbide coatings are distinguished by high hardness, low porosity, and good wear resistance compared to other thermal spray technologies. However, for many engineering applications the ductility and fatigue resistance are the most important material properties. In the use of HVOF systems, these properties are influenced by many boundary conditions. This paper presents the effects of different spraying parameters on the fatigue resistance of samples coated by the HVOF process.